Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lgr5  leucine rich repeat containing G protein coupled receptor 5   (Synonyms: Gpr49)
Results	Reference
1*	J:51995 Hermey G, Methner A, Schaller HC, Hermans-Borgmeyer I, Identification of a novel seven-transmembrane receptor with homology to glycoprotein receptors and its expression in the adult and developing mouse. Biochem Biophys Res Commun. 1999 Jan 8;254(1):273-9
1*	J:210988 Kawasaki M, Porntaveetus T, Kawasaki K, Oommen S, Otsuka-Tanaka Y, Hishinuma M, Nomoto T, Maeda T, Takubo K, Suda T, Sharpe PT, Ohazama A, R-spondins/Lgrs expression in tooth development. Dev Dyn. 2014 Jun;243(6):844-51
1	J:264609 Li J, Yuan Y, He J, Feng J, Han X, Jing J, Ho TV, Xu J, Chai Y, Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion. Dev Biol. 2018 Sep 1;441(1):191-203
1	J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7
1*	J:262420 Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefevre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Basaran S, Yucel EB, Tan TT, Vlaeminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B, RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018 May;557(7706):564-569
1	J:332922 Venkata VD, Jamaluddin MFB, Goad J, Drury HR, Tadros MA, Lim R, Karakoti A, O'Sullivan R, Ius Y, Jaaback K, Nahar P, Tanwar PS, Development and characterization of human fetal female reproductive tract organoids to understand Mullerian duct anomalies. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2118054119
1	J:290543 Vidal VP, Jian-Motamedi F, Rekima S, Gregoire EP, Szenker-Ravi E, Leushacke M, Reversade B, Chaboissier MC, Schedl A, R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors. Elife. 2020 May 1;9:e53895
1*	J:341172 Watanabe K, Horie M, Hayatsu M, Mikami Y, Sato N, Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon. Gene Expr Patterns. 2023 Sep;49:119333